Author

Masamichi Ito

The University of TokyoORCID 0000-0001-6945-3137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Research Focus:benchmarking· 2 Approach:deep learning· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Sosuke Hosokawa· 3 shared Toshinaru KawakamiiD· 3 shared Atsumasa KurozumiiD· 2 shared Norihiko TakedaiD· 2 shared Ryohei Tanaka· 2 shared Satoshi KoderaiD· 2 shared Shun MinatsukiiD· 2 shared Takayuki IsagawaiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersBioinformatics

Sosuke Hosokawa

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 15, 2026

REN-former prioritizes candidate regulators of kidney disease-state transitions through single-cell foundation modeling and human genetics

Imari Mimura, Sosuke Hosokawa, Yosuke Hirakawa…·Masaomi Nangaku

REN-former identifies gene regulators of kidney disease transitions by combining single-cell modeling and human genetics.

DOI 10.64898/2026.09.10.746481

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BioinformaticsPLoS ONEPeer-reviewedMar 6, 2026

PAH-former: Transfer Learning for Efficient Discovery of Pulmonary Arterial Hypertension-Associated Genes

Toshinaru Kawakami, Sosuke Hosokawa, Masamichi Ito…·Norihiko Takeda

PAH-former uses transfer learning with Geneformer to identify PAH-associated genes by fine-tuning on public PAH lung tissue data and performing in silico perturbation analysis.

DOI 10.1371/journal.pone.0344084

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Cell BiologybioRxivPreprintJan 30, 2026

The REFLEX system enables in vivo identification of perivascular angiogenic macrophages in the heart

Tatsuyuki Sato, Takayuki Isagawa, Toshinaru Kawakami…·Norihiko Takeda

The paper develops REFLEX and HUNTERuni-seq to identify perivascular angiogenic macrophages (PVAMs) that deliver VEGF-A to endothelial cells, showing physical contact is critical for effective signaling.

DOI 10.64898/2026.01.27.702189

𝕏 PostBluesky