Author

Sosuke Hosokawa

The University of Tokyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Research Focus:benchmarking· 2 Approach:deep learning· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Masamichi ItoiD· 3 shared Toshinaru KawakamiiD· 3 shared Atsumasa KurozumiiD· 2 shared Norihiko TakedaiD· 2 shared Ryohei Tanaka· 2 shared Satoshi KoderaiD· 2 shared Shun MinatsukiiD· 2 shared Takayuki IsagawaiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersBioinformatics

Masamichi ItoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

REN-former prioritizes candidate regulators of kidney disease-state transitions through single-cell foundation modeling and human genetics

Imari Mimura, Sosuke Hosokawa, Yosuke Hirakawa, Toshinaru Kawakami, Yu Kurata, Masamichi Ito, Tetsuhiro Tanaka, Satoshi Kodera, Norihiko Takeda, Masaomi Nangaku

REN-former identifies gene regulators of kidney disease transitions by combining single-cell modeling and human genetics.

bioRxiv · Sep 15, 2026 · PreprintBioinformatics

PAH-former: Transfer Learning for Efficient Discovery of Pulmonary Arterial Hypertension-Associated Genes

Toshinaru Kawakami, Sosuke Hosokawa, Masamichi Ito, Atsumasa Kurozumi, Ryohei Tanaka, Shun Minatsuki, Junichi Ishida, Takayuki Isagawa, Satoshi Kodera, Norihiko Takeda

PAH-former uses transfer learning with Geneformer to identify PAH-associated genes by fine-tuning on public PAH lung tissue data and performing in silico perturbation analysis.

PLoS ONE · Mar 6, 2026Peer-reviewedBioinformatics

The REFLEX system enables in vivo identification of perivascular angiogenic macrophages in the heart

Tatsuyuki Sato, Takayuki Isagawa, Toshinaru Kawakami, Sosuke Hosokawa, Masamichi Ito, Daigo Sawaki, Shigeru Sato, Yu Nakagama, Kazutoshi Ono, Ariunbold Chuluun-Erdene, Thuc Toan Pham, Ryohei Tanaka, Atsumasa Kurozumi, Hiroaki Semba, Masaki Wake, , Norihiko Takeda

The paper develops REFLEX and HUNTERuni-seq to identify perivascular angiogenic macrophages (PVAMs) that deliver VEGF-A to endothelial cells, showing physical contact is critical for effective signaling.

bioRxiv · Jan 30, 2026 · PreprintCell Biology