Author

Chen Eitan

Weizmann Institute of ScienceORCID 0000-0001-6952-0336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Eran HornsteiniD· 3 shared Johnathan Cooper‐KnockiD· 3 shared Ammar Al‐ChalabiiD· 2 shared Aviad SianyiD· 2 shared Hagai Marmor-Kollet· 2 shared Jan Herman VeldinkiD· 2 shared Kevin Patrick KennaiD· 2 shared Leonard H. van den BergiD· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Eran HornsteinORCID

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3 papers

Recent·Most cited

GenomicsNeuronPeer-reviewedJan 18, 2022

Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis

Sai Zhang, Johnathan Cooper‐Knock, Annika K K Weimer…·Michael P. Snyder

This study identifies 690 candidate ALS genes using a hierarchical Bayesian model, highlighting genetic convergence on the distal axon and functional significance in motor neurons.

116 citationstop 1%

humanwhole-genome sequencing

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NeurosciencebioRxivPreprintJun 3, 2021

Non-Coding Genetic Analysis Implicates Interleukin 18 Receptor Accessory Protein 3'UTR in Amyotrophic Lateral Sclerosis

Chen Eitan, Aviad Siany, Elad Barkan…·Eran Hornstein

The paper identifies non-coding variants in the IL18RAP 3'UTR that reduce ALS risk by modulating neuro-inflammation through NF-κB signaling in microglia.

2 citations

humanwhole-genome sequencing

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Molecular BiologyMolecular CellPeer-reviewedNov 19, 2020

Spatio-temporal Proteomic Analysis of Stress Granule disassembly using APEX Reveals Regulation by SUMOylation and links to ALS pathogenesis

Hagai Marmor-Kollet, Aviad Siany, Nancy Kedersha…·Eran Hornstein

This study uses APEX proximity-proteomics to analyze the spatio-temporal proteomic changes during stress granule disassembly, identifying novel proteins and revealing SUMOylation's role in ALS pathogenesis.

253 citationstop 1%

humanproteomics

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