Author

Elad Barkan

Weizmann Institute of ScienceORCID 0000-0002-6176-3293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:metagenomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Daphna RothschildiD· 3 shared Eran SegaliD· 3 shared Omer WeissbrodiD· 3 shared Alexander KurilshikoviD· 2 shared Cisca WijmengaiD· 2 shared Jingyuan FuiD· 2 shared Ad MascleeiD· 1 shared Adina WeinbergeriD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersGenetics

Daphna RothschildORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Non-Coding Genetic Analysis Implicates Interleukin 18 Receptor Accessory Protein 3'UTR in Amyotrophic Lateral Sclerosis

Chen Eitan, Aviad Siany, Elad Barkan, Tsviya Olender, Kristel R. van Eijk, Matthieu Moisse, Sali M.K. Farhan, Yehuda Matan Danino, Eran Yanowski, Hagai Marmor-Kollet, Natalia Rivkin, Nancy‐Sarah Yacovzada, Shu‐Ting Hung, Johnathan Cooper‐Knock, Chien‐Hsiung Yu, , Eran Hornstein

The paper identifies non-coding variants in the IL18RAP 3'UTR that reduce ALS risk by modulating neuro-inflammation through NF-κB signaling in microglia.

bioRxiv · Jun 3, 2021 · PreprintNeuroscience

Large-scale association analyses identify host factors influencing human gut microbiome composition

Alexander Kurilshikov, Carolina Medina‐Gómez, Rodrigo Bacigalupe, Djawad Radjabzadeh, Jun Wang, Ayşe Demirkan, Caroline Ivanne Le Roy, Juan A. Raygoza Garay, Casey T. Finnicum, Xingrong Liu, Daria V. Zhernakova, Marc Jan Bonder, Tue H. Hansen, Fabian Frost, Malte Christoph Rühlemann, , Oluf Borbye Pedersen

The paper identifies 31 host genetic loci influencing gut microbiome composition through GWAS and suggests causal effects in inflammatory diseases.

Nature Genetics · Jan 18, 2021Peer-reviewedGenetics

Environmental factors dominate over host genetics in shaping human gut microbiota composition

Daphna Rothschild, Omer Weissbrod, Elad Barkan, Alexander Kurilshikov, Tal Korem, David Zeevi, Paul Igor Costea, Anastasia Godneva, Iris N. Kalka, Noam Bar, Smadar Shilo, Dar Lador, Arnau Vich Vila, Niv Zmora, Meirav Pevsner‐Fischer, , Eran Segal

This study shows environmental factors have a greater impact on human gut microbiota than host genetics, with microbiome data adding significant predictive value to phenotypes.

Nature · Feb 28, 2018Peer-reviewedGenetics