Author

Stephen P. Chapman

Centre National de la Recherche ScientifiqueORCID 0000-0001-6982-4591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Arnaud MourieriD· 2 shared Bianca Hermine HabermanniD· 2 shared Élisabeth RémyiD· 1 shared Estelle DupreziD· 1 shared Theo Brunet· 1 shared Thibaut MoliniéiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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2 shared papersSystems Biology

Arnaud MourierORCID

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3 papers

Recent·Most cited

MitoMAMMAL: a genome scale model of mammalian mitochondria predicts cardiac and BAT metabolism

Stephen P. Chapman, Theo Brunet, Arnaud Mourier, Bianca Hermine Habermann

MitoMAMMAL predicts cardiac and BAT metabolism in mouse and human by integrating proteomic and transcriptomic data with a genome-scale mitochondrial metabolic model.

Bioinformatics Advances · Nov 3, 2024Peer-reviewedSystems Biology

Logical modelling of myelofibrotic microenvironment predicts dysregulated progenitor stem cell crosstalk

Stephen P. Chapman, Estelle Duprez, Élisabeth Rémy

The paper constructs a logical model of the myelofibrotic microenvironment to predict how TPO and TLR signaling disrupt stem cell crosstalk and drive disease progression.

Biosystems · Sep 1, 2023Peer-reviewedSystems Biology

MitoMouse is a model reconstruction of murine mitochondrial metabolism

Stephen P. Chapman, Thibaut Molinié, Arnaud Mourier, Bianca Hermine Habermann

The paper develops a mouse-specific mitochondrial metabolic model called mitoMouse, validated to accurately model CoQ reduction in response to increased malate import.

bioRxiv · Jan 2, 2023 · PreprintSystems Biology