Arnaud Mourier

The paper identifies a female-specific microglial redox program that influences susceptibility to obesity by modulating metabolic resilience and mTORC1 signaling.

This paper introduces secondary antibodies conjugated to lipophilic ATTO dyes for high-density membrane labeling in super-resolution and expansion microscopy, enabling precise organelle visualization.

The paper identifies a tissue-specific mitochondrial isoform of MFN2 generated by non-coding exon splicing and shows its distinct functional role in lipid trafficking.

This study investigates the role of If1 inhibitory peptides in Saccharomyces cerevisiae, showing they prevent ATP hydrolysis under glyco-oxidative stress and stabilize the F1 subcomplex.

This paper develops a cellular assay to assess MFN2 variants' fusion capacity in CMT2A and shows correlation with computational predictions.

MitoMAMMAL predicts cardiac and BAT metabolism in mouse and human by integrating proteomic and transcriptomic data with a genome-scale mitochondrial metabolic model.

This study shows that increased POLRMT levels enhance mitochondrial transcription initiation but do not increase OXPHOS biogenesis due to downstream regulatory limitations.

This study shows that mice with reduced respirasomes maintain normal bioenergetics and physiology, suggesting respirasomes are not essential for basic function but may have other roles.

The paper develops a mouse-specific mitochondrial metabolic model called mitoMouse, validated to accurately model CoQ reduction in response to increased malate import.