Bianca Hermine Habermann

The paper introduces DiscOperon, a tool for predicting operon structures in bacterial genomes, and applies it to Mycococcus xanthus, demonstrating its effectiveness across multiple species.

The paper identifies a tissue-specific mitochondrial isoform of MFN2 generated by non-coding exon splicing and shows its distinct functional role in lipid trafficking.

mitoXplorer 3.0 provides new tools for analyzing mitochondrial variability in single-cell RNA-seq data, with applications in understanding mitochondrial dysfunction in disease.

MitoMAMMAL predicts cardiac and BAT metabolism in mouse and human by integrating proteomic and transcriptomic data with a genome-scale mitochondrial metabolic model.

The paper identifies a titin-dependent biomechanical feedback mechanism that adjusts sarcomere structure to meet the functional demands of different insect muscle types.

This study identifies Tono as a mechanically responsive transcriptional regulator that controls sarcomere maturation through liquid-liquid phase separation in Drosophila muscle development.

This study uses single-cell RNA sequencing to identify brown fat precursors and demonstrates their in vitro differentiation into functional brown adipocytes.

The paper infers cell cycle phases from a partially temporal network of protein interactions in budding yeast, showing that partial temporal data can reveal temporal organization.

The paper develops a mouse-specific mitochondrial metabolic model called mitoMouse, validated to accurately model CoQ reduction in response to increased malate import.

The paper introduces evo-MOTiF, a pipeline and database for analyzing protein motif evolution, revealing weak negative correlation between disorder and conservation in SLiMs.

This study shows that mechanical tension drives multi-scale self-organisation in human iPSC-derived muscle fibers by coordinating sarcomere assembly and myofiber bundling.

The paper updates the mitoXplorer platform to integrate mitochondrial expression dynamics with cellular context, introducing new functions for network analysis and transcription factor enrichment.

AnnoMiner integrates epigenetic, transcription factor, and transcriptomics data to predict transcriptional regulators without requiring chromatin data from the same process.

This study identifies the Hippo pathway's role in regulating sarcomeric gene expression to control myofibril assembly and muscle fiber growth in Drosophila.

mitoXplorer is a web-based platform that integrates and visualizes mitochondrial gene expression and mutation data across multiple datasets to uncover regulatory differences in mitochondrial dynamics.

The paper identifies a biphasic mode of sarcomere development in Drosophila flight muscles, regulated by Spalt major, with distinct phases of assembly and maturation.

This paper identifies Atf3 as a gene regulated by disrupted cell polarity in Drosophila, showing its role in cytoskeleton organization and epithelial differentiation.

The paper identifies DNA motifs at TAD boundaries in flies and shows they encode 3D genome architecture, with an online database for exploration.