Andrew Duncan

Temporal chromatin and transcriptome dynamics driven by JUND and progesterone receptor binding in the pregnant mouse myometrium

The paper identifies JUND and progesterone receptor binding dynamics in the pregnant mouse myometrium, linking chromatin accessibility changes to gene expression during pregnancy, labor, and postpartum.

Evolutionary conditioning enables guided generation of functionally diverse enhancers

This paper introduces EnhancAR, a deep learning model that generates functionally diverse enhancers using evolutionary homologs instead of cell type labels.