Stefan Johannes Karl Krauss

This paper develops a humanized bile duct chip to model cholangiopathies and test treatments, showing drug effects and disease phenotypes.

This study shows that the TNKS inhibitor OM-153 reduces fibrosis markers and ECM expression in multiple preclinical IPF models by inhibiting WNT/β-catenin and YAP signaling.

The paper describes a modular co-aggregation strategy to recreate embryonic-extraembryonic interactions in vitro, leading to more complex gastruloid morphotypes with improved lineage diversity and patterning.

This study creates a comprehensive single-cell transcriptomic atlas of human endothelial cells across adult life, identifying age-related transcriptional changes and a p21-linked senescence program.