Oskari Lehtonen

The paper identifies nine transcriptional programs driving metastasis in ovarian cancer using multi-modal data from 350 tumor samples, highlighting intra-patient heterogeneity and therapeutic implications.

Histolytics provides a framework for interpretable spatial analysis of histopathology images, enabling high-resolution characterization of tissue structures and features.

The paper introduces an interactive workflow called Cyto for analyzing mass cytometry data, demonstrating its ability to capture immune cell sub-populations and tumor compositions in blood and ovarian cancer samples.