Author

Essi Kahelin

University of HelsinkiORCID 0009-0005-4518-5728Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2

Frequent Co-Authors

Anni VirtaneniD· 3 shared Ada JunqueraiD· 2 shared Anna VähärautioiD· 2 shared Anniina FärkkiläiD· 2 shared Fernando Pérez‐VillatoroiD· 2 shared Foteini ChamchougiaiD· 2 shared Iga NiemieciD· 2 shared Jaana OikkoneniD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Anni VirtanenORCID

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3 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedFeb 9, 2026

✦ In-depth digest

Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes

Fernando Pérez‐Villatoro, Aleksandra Shabanova, Lilian van Wagensveld…·Anniina Färkkilä

Cyclic immunofluorescence of 265 high-grade serous ovarian carcinomas and random-forest feature ranking identify cancer-cell MHC-II as an adjusted predictor of longer survival marking immune-activated tumor-stroma hotspots.

10 citationstop 1%

humanimaging

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Cancer BiologybioRxivPreprintAug 26, 2025

Multi-modal characterization of transcriptional programs that drive metastatic cascades to solid sites and ascites in ovarian cancer

Kaiyang Zhang, Essi Kahelin, Giovanni Marchi…·Sampsa Hautaniemi

The paper identifies nine transcriptional programs driving metastasis in ovarian cancer using multi-modal data from 350 tumor samples, highlighting intra-patient heterogeneity and therapeutic implications.

1 citation

humanbulk RNA-seq

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Cancer BiologyCancer CellPeer-reviewedDec 1, 2024

Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer

Inga-Maria P. Launonen, Iga Niemiec, María Mercedes Hincapié-Otero…·Anniina Färkkilä

This study shows chemotherapy causes myeloid-driven spatial T-cell exhaustion in ovarian cancer by altering immune cell states and interactions, suggesting new immunotherapy approaches.

103 citationstop 1%

humanscRNA-seq

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