Sandrine Marquet

The paper uses single-cell RNA sequencing to analyze immune cell interactions in asymptomatic and symptomatic malaria patients, finding reduced monocyte-T cell interactions and increased inflammation in symptomatic cases.

The paper identifies and functionally characterizes regulatory variants in DPP9 associated with severe COVID-19 by analyzing genetic risk factors and their impact on gene expression and immune cell function.

The paper identifies a dual-function regulatory element and a malaria risk variant that interact epistatically to influence T-cell activation and severe malaria susceptibility.

The paper identifies functional genetic variants in the ATP2B4 regulatory region associated with severe malaria and demonstrates their impact on gene expression and calcium homeostasis.