Magali Torres

The paper uses single-cell RNA sequencing to analyze immune cell interactions in asymptomatic and symptomatic malaria patients, finding reduced monocyte-T cell interactions and increased inflammation in symptomatic cases.

The paper identifies and functionally characterizes regulatory variants in DPP9 associated with severe COVID-19 by analyzing genetic risk factors and their impact on gene expression and immune cell function.

The paper identifies genes and secreted proteins modulated by High Fat and High Sugar diets in Drosophila hearts, revealing adaptive responses to nutritional stress.

The paper identifies exonic enhancers as dual-function regulatory elements that influence gene expression and are associated with disease and evolution.

The paper identifies Epromoters as cis-regulatory elements that regulate clusters of stress-response genes by recruiting key transcription factors, showing their role across different stress models.

The paper identifies a dual-function regulatory element and a malaria risk variant that interact epistatically to influence T-cell activation and severe malaria susceptibility.

The paper identifies genetic networks and regulatory elements associated with cardiac performance variation in Drosophila and finds conserved genetic architecture between flies and humans.

The paper identifies functional genetic variants in the ATP2B4 regulatory region associated with severe malaria and demonstrates their impact on gene expression and calcium homeostasis.

The paper compares the transcriptional response in a sepsis mouse model to human sepsis patients and identifies a shared molecular signature.