Author

Edwin V. Pozharski

University of Maryland, BaltimoreORCID 0000-0001-7012-5376Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Dung Ngoc Pham NguyeniD· 2 shared Marzena PazgieriD· 2 shared William David TolbertiD· 2 shared Abdolrahim Abbasi· 1 shared Alicia SatoiD· 1 shared Alonso HerediaiD· 1 shared Andrés FinziiD· 1 shared Andrew Asakawa· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioengineering

Dung Ngoc Pham NguyenORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringStructurePeer-reviewedMay 14, 2025

A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV

Mohammad M. Sajadi, Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani…·Anthony L. DeVico

This study engineers an HIV broadly neutralizing antibody to improve its potency, antiviral activity, and manufacturability while maintaining safety and efficacy.

11 citationstop 4%

humanproteomics

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BiochemistrybioRxivPreprintJan 28, 2025

Heartbeat-like dynamics drives oxygen activation in methane monooxygenase

Yunha Hwang, Bumhan Ryu, Dong-Heon Lee…·Seung Jae Lee

This paper presents a 2.85 Å cryo-EM structure of MMOH-MMOB, revealing conformational changes and Fe-Fe distances critical for oxygen activation in methane monooxygenase.

DOI 10.1101/2025.01.28.635075

cryo-EMexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedOct 23, 2023

Structure-function Analyses Reveal Key Molecular Determinants of HIV-1 CRF01_AE Resistance to the Entry Inhibitor Temsavir

Jérémie Prévost, Yaozong Chen, Fei Zhou…·Marzena Pazgier

This study identifies multiple molecular determinants of HIV-1 CRF01_AE resistance to temsavir, showing that resistance involves crosstalk between His375 and inner domain layers.

13 citations

humanproteomics

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