Curt Waltmann

This study uses molecular dynamics simulations to show that IN-RNA filaments guide HIV-1 capsid assembly and shape, with octameric filaments forming more conical capsids than tetrameric ones.

The paper shows that IRSp53 assists HIV-1 assembly by interacting with Gag and extending its conformation, which is validated through simulations and experiments.

This study shows that altering charge on bacterial microcompartment shell proteins can control their self-assembly into tubular structures.

This study uses molecular simulations to show that lenacapavir disrupts HIV-1 capsid assembly by altering hexamer/pentamer ratios and impairing RNA encapsidation.