Matthias J.P. van Osch

This paper introduces a method to map human cortical vasculature at high resolution, enabling quantitative analysis of vascular networks in human brain tissue.

This study simulates BOLD fMRI signals across cortical depth using realistic 3D vascular models to assess how vascular architecture influences GE and SE BOLD contrast.

The paper presents a computational framework to simulate BOLD fMRI signal formation in a synthetic human 3D cortical vasculature model, showing that human-specific features significantly affect the BOLD fingerprint.

This study investigates the effects of long-term sleep disruption on brain biomarkers in maritime pilots and finds no evidence of preclinical Alzheimer's disease markers compared to healthy controls.

The paper uses two non-contrast MRI methods to investigate the glymphatic system's response to sleep and aging in humans.

This study directly measures the light response of the human SCN and finds that light suppresses SCN activity across multiple wavelengths, suggesting a need to revise light exposure strategies.

ExploreASL provides a standardized image processing pipeline for multi-center ASL MRI studies, improving reproducibility and enabling group-level statistical analysis across diverse clinical populations.