Author

Michael A. Trakselis

Baylor UniversityORCID 0000-0001-7054-8475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Andrew J. SnyderiD· 1 shared Chuxuan LiiD· 1 shared Colin ToiD· 1 shared David R. McKinzeyiD· 1 shared Desmond C. OkaforiD· 1 shared Rashini Y. Baragama ArachchiiD· 1 shared Temitope M AdelekeiD· 1 shared Yang GaoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

Andrew J. SnyderORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 23, 2026

Structural Activation of DNA Unwinding by MCM8/9/HROB

Chuxuan Li, Colin To, Temitope M Adeleke…·Michael A. Trakselis

This study presents dynamic structures of MCM8/9 with DNA, HROB, and ATP analogs to elucidate the mechanism of MCM8/9 DNA unwinding and activation by HROB.

DOI 10.64898/2026.04.28.721408

structural biologyexperimental assay

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Cell BiologyDNA repairPeer-reviewedNov 1, 2025

MCM8/9 and FANCD2 interact within a shared pathway in response to replication stress caused by DNA crosslinks

Rashini Y. Baragama Arachchi, Desmond C. Okafor, Andrew J. Snyder, Michael A. Trakselis

This study shows MCM8/9 interacts with FANCD2 during ICL repair, functions in the same pathway, and their loss is epistatic with no additive DNA damage.

2 citations

humanproteomics

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