Author

Sirkku Pollari

Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0001-7066-7052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrey A. BobkoviD· 2 shared Eduard A. SergienkoiD· 2 shared Alon Rabinovich· 1 shared Alondra Schweizer BurgueteiD· 1 shared Annie LeeiD· 1 shared Badri Narayan VardarajaniD· 1 shared Beatrice Acheson· 1 shared Chen-Ting Ma· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Andrey A. BobkovORCID

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2 papers

Recent·Most cited

NeuroscienceDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedJul 1, 2026

CD33 and Clusterin Interact Biophysically and Genetically to Modulate Alzheimer Risk

Roger B. Dodd, Masahiro Enomoto, Ye Zhou…·Peter St George‐Hyslop

This study shows how non-coding variants in CD33 affect Alzheimer's risk by altering CD33M dimerization and interactions with clusterin and Aβ, impacting microglial function.

1 citationtop 5%

humanproteomics

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BiochemistryJournal of Molecular BiologyPeer-reviewedJun 9, 2026

Uncompetitive Allosteric Inhibitor of Mitochondrial Creatine Kinase Prevents Binding and Release of Creatine by Stabilization of Loop Closure

Merve Demir, Chen-Ting Ma, Nikhil Puvvula…·Eduard A. Sergienko

The paper identifies an uncompetitive allosteric inhibitor of mitochondrial creatine kinase that stabilizes loop closure, preventing creatine binding and phosphocreatine release.

DOI 10.1016/j.jmb.2026.169896

humanexperimental assay

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