Alexander Mahnert

The paper develops a framework to predict microbial survival traits in spacecraft cleanrooms using metagenomics and machine learning, showing trait variability within taxa and the need for functional assessment beyond taxonomy.

The paper identifies Nitrosocosmicus species as commensals in the human skin microbiome through cultivation and genomic analysis, showing their adaptation to skin environments.

This study analyzes the ISS microbiome over seven years, revealing stable core communities with localized microevolution and AMR/virulence dynamics that require functional validation.

This study identifies Methanobrevibacter smithii as associated with colorectal cancer through trophic interactions with CRC-causing bacteria and archaeal-derived compounds.

The paper isolates and characterizes two new Methanobrevibacter species from human feces, highlighting genomic and phenotypic differences.

This study examines age-related changes in methanogenic archaea in the human gut microbiome, finding that centenarians have a methanogen composition similar to younger adults and that Ca. M. intestini plays a key role in network stability.

This study examines the development of oral and gastrointestinal microbiomes in infants, showing that breastfeeding influences the maturation of anaerobic and archaeal communities.

This study identifies cachexia-associated microbial metabolites using computational modeling and metabolomic analyses in a murine cancer model.

This study isolates and characterizes novel Methanobrevibacter strains from human fecal samples, expanding the cultivated archaeome and linking them to gastrointestinal health.

The paper analyzes 1,167 archaeal genomes from the human gut to reveal novel species, genomic adaptations, and correlations with socio-demographic factors.

The study analyzes the microbial environment of the ISS, finding it similar to Earth's confined spaces, with microorganisms adapted to the extreme environment but not causing genomic changes relevant to human health.