Guillaume Borrel

This study shows that archaeal cell envelopes activate innate immunity via TLR2, unlike bacteria which use multiple PRRs.

This study identifies Hib, a new family of ribosome hibernation factors in Archaea, showing its role in preserving ribosomes during stress and revealing its structural and functional mechanisms.

This study characterizes DNA-carrying extracellular vesicles (EVs) from Methanobrevibacter smithii, revealing their role in DNA and protein export in the gut.

This study enables formate-dependent methanogenesis in Methanosarcina acetivorans through metabolic engineering and adaptive evolution, expanding its substrate utilization capabilities.

The paper confirms a new archaeal genetic code (Code 34) where TAG codons encode pyrrolysine, showing sporadic distribution and lateral gene transfer.

The paper analyzes 1,167 archaeal genomes from the human gut to reveal novel species, genomic adaptations, and correlations with socio-demographic factors.