Jun Lin

This study uses single-cell RNA sequencing to analyze immune responses in COVID-19 patients, identifying key immune cell changes and molecular pathways linked to disease severity.

The paper uses single-cell analysis to show that Tocilizumab reduces monocyte-driven inflammation in severe COVID-19 but does not fully suppress immune responses.

APEC improves single-cell chromatin accessibility analysis by clustering cells based on accessible regions and integrates with other tools to enhance clustering accuracy and predict gene expression and regulatory elements.