Kun Li

The paper identifies two transcription factor clusters regulating NK cell differentiation and highlights FOSL2 and EGR2 as essential for NK cell maturation and function.

The paper uses single-cell analysis to show that Tocilizumab reduces monocyte-driven inflammation in severe COVID-19 but does not fully suppress immune responses.

APEC improves single-cell chromatin accessibility analysis by clustering cells based on accessible regions and integrates with other tools to enhance clustering accuracy and predict gene expression and regulatory elements.