Chuang Guo

The paper constructs a lifespan single-cell atlas of immune cells, identifies an early-childhood immunometabolic transition around age 6, and develops an age-referenced framework for immune-state analysis.

The paper analyzes single-cell transcriptomes from healthy human endometrium across reproductive stages to understand immune cell dynamics and identify potential biomarkers for reproductive diseases.

This study uses single-cell RNA sequencing to analyze immune responses in COVID-19 patients, identifying key immune cell changes and molecular pathways linked to disease severity.

The paper uses single-cell analysis to show that Tocilizumab reduces monocyte-driven inflammation in severe COVID-19 but does not fully suppress immune responses.