Author

Rashmi Patel

National Cancer InstituteORCID 0000-0001-7090-7044Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Susan MackemiD· 2 shared Anna Trofka· 1 shared Brian D. HarfeiD· 1 shared Jianjian Zhu· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersDevelopmental Biology

Susan MackemORCID

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2 papers

Recent·Most cited

Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 23, 2025

Dual Bmp-negative feedback loops modulate both AER and ZPA function to buffer and constrain postaxial digit number.

Rashmi Patel, Susan Mackem

This study identifies dual Bmp-negative feedback loops that regulate AER and ZPA function to constrain postaxial digit number to the pentadactyl state in vertebrates.

1 citation

mouseexperimental assay

𝕏 PostBluesky

Developmental BiologyDevelopmental CellPeer-reviewedAug 16, 2022

Sonic Hedgehog is not a limb morphogen but acts as a trigger to specify all digits.

Jianjian Zhu, Rashmi Patel, Anna Trofka…·Susan Mackem

This study shows Sonic Hedgehog (Shh) acts as a trigger for digit specification through a relay network rather than as a traditional morphogen.

40 citations

mouseexperimental assay

𝕏 PostBluesky