Author

Jianjian Zhu

National Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Susan MackemiD· 3 shared Anna Trofka· 2 shared Aimée ZúñigaiD· 1 shared Álvaro Rada-IglesiasiD· 1 shared Angela MorabitoiD· 1 shared Aušra GirdžiušaitėiD· 1 shared Axel ViseliD· 1 shared Brandon ChacóniD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersDevelopmental Biology

Susan MackemORCID

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3 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedJul 6, 2023

A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2

Marta Losa, Iros Barozzi, Marco Osterwalder…·Licia Selleri

The paper reconstructs a gene regulatory network directed by PBX1/2 and HAND2 in mouse limb development, showing their genetic interaction and tissue-specific function.

18 citations

mousebulk RNA-seq

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Developmental BiologyDevelopmental CellPeer-reviewedAug 16, 2022

Sonic Hedgehog is not a limb morphogen but acts as a trigger to specify all digits.

Jianjian Zhu, Rashmi Patel, Anna Trofka…·Susan Mackem

This study shows Sonic Hedgehog (Shh) acts as a trigger for digit specification through a relay network rather than as a traditional morphogen.

40 citations

mouseexperimental assay

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Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 2, 2020

Mutual transcriptional repression between Gli3 and Hox13 genes determines the anterior-posterior asymmetry of the autopod

María Félix Bastida, Rocío Pérez‐Gómez, Anna Trofka…·María A. Ros

The paper investigates how mutual repression between Gli3 and Hox13 genes determines the anterior-posterior asymmetry of the autopod, explaining digit 1 agenesis in Hoxa13 mutants.

28 citations

mousestatistical model

𝕏 PostBluesky