Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles
Dorival Mendes Rodrigues‐Junior, Ana Rosa Sáez-Ibáñez, Julia M. Scheffler, Takeshi Terabayashi, Nina Daubel, Taija Mäkinen, Olof Idevall‐Hagren, Aristidis Moustakas, Ingvar Ferby
The paper shows that ErbB3 regulates Integrin β1 trafficking, redirecting it from recycling to lysosomal degradation and EV secretion when ErbB3 is lost, affecting cell migration.
The Journal of Cell Biology · Oct 14, 2025Peer-reviewedCell Biology