MicrobiologybioRxivPreprint
Pneumococcus drives STAT3 activation of lower airway epithelium in a strain and burden-dependent manner
Anna Both, Christine Chevalier, Michael G. Connor, Mélanie Anne Hamon
This study shows that Streptococcus pneumoniae strain TIGR4 activates canonical STAT3 and suppresses non-canonical STAT3 in a burden-dependent manner, while strain 6B ST90 requires higher burden for minimal STAT3 response.
DOI 10.64898/2026.02.13.705726