Daniela Schlatzer

This study analyzes phosphoproteome dysregulation in 5XFAD mice, identifying sex-specific and temporal patterns, novel biomarkers, and a key kinase pathway involved in Alzheimer's disease progression.

RokaiXplorer provides an intuitive web tool for phospho-proteomic data analysis and visualization, offering multiple functionalities and interactive features for researchers without specialized training.

This paper introduces RoKAI, a network-based framework that improves kinase activity inference by integrating functional information, showing enhanced accuracy and robustness in identifying dysregulated kinases in diseases.

This paper shows that reducing PLP1 expression in a mouse model of PMD improves myelination, motor function, and lifespan, supporting PLP1 suppression as a therapeutic strategy.

CoPhosK predicts kinase-substrate associations using co-phosphorylation analysis from mass spectrometry data, improving prediction performance and expanding the known landscape of kinase-substrate interactions.