Lilianne Barbar

This study shows that enhancing mitochondrial NAD+ import through SLC25A51 protects neurons from SARM1-driven degeneration by preventing coupled metabolic failure.

The paper uses iPSC-derived glia cultures from MS patients to identify glia-intrinsic disease mechanisms and potential therapeutic targets.

This study examines the effects of microgravity on iPSC-derived neural organoids using samples from the International Space Station, finding reduced cell proliferation and increased neural maturity in space-cultured organoids.

This paper shows that reducing PLP1 expression in a mouse model of PMD improves myelination, motor function, and lifespan, supporting PLP1 suppression as a therapeutic strategy.

This study identifies CD49f as a marker to isolate functional human iPSC-derived astrocytes, which can be stimulated to exhibit a neurotoxic phenotype relevant to neurodegenerative diseases.