Giorgia Benegiamo

This study maps proteome-wide QTLs in a MASLD mouse model to construct gene-protein-phenotype metabolic networks, identifying Ubr1 as a central regulator of proteostasis and lipid metabolism.

The paper identifies genetic and dietary factors influencing intestinal inflammation in BXD mice, finding MUC4 and EPHA6 as potential mediators of IBD susceptibility.

This study examines how genetic background and sex influence metabolic responses to high-fat diet in mice, highlighting the role of mitochondrial function in physiological diversity.

This paper demonstrates that gene replacement therapy using AAV-PHP.B vector improves survival and corrects metabolic and behavioral deficits in a mouse model of Leigh syndrome.