Yu Kong

Naturally occurring Alzheimer's disease in rhesus monkeys

This study identifies naturally occurring Alzheimer's disease in aged rhesus monkeys, showing cognitive impairments and AD pathological hallmarks.

Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data

The paper uses deep learning to analyze electron microscopy data from mouse auditory cortex, revealing structural changes in synapses and mitochondria associated with fear memory.

Insights from deconvolution of cell subtype proportions enhance the interpretation of functional genomic data.

The paper shows that estimating cell subtype proportions from functional genomic data improves interpretation of human phenotypic associations by revealing cellular events.

Genetic variants influence on the placenta regulatory landscape

The paper investigates how genetic variants affect gene expression and DNA methylation in human placentas, revealing interaction profiles and providing a reference for future studies.

Mosaic Chromosomal Aneuploidy Detection By Sequencing (MAD-seq)

MAD-seq detects low-level mosaic chromosomal aneuploidy using a new sequencing assay and analysis method, revealing previously unrecognized aneuploidy in public datasets.

Intragenomic Redistribution Of Host Transcription Factor Binding With Toxoplasma gondii Infection

This study investigates how Toxoplasma gondii infection alters host transcriptional regulation by redistributing AP-1 transcription factor binding, leading to changes in chromatin accessibility and gene expression.