Author

Christopher McCrae

AstraZeneca (United States)ORCID 0000-0001-7184-9069Unclaimed ORCID profile · follow to get notified of new preprints

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Christopher McCrae2 papers

Biology Disciplines

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Aadil AhmediD· 1 shared Adrian Pablo MansiniiD· 1 shared Bethany E. Perez WhiteiD· 1 shared Christian Fernando Guerrero‐JuareziD· 1 shared Christopher D. NazaroffiD· 1 shared Connor ColeiD· 1 shared Enno SchmidtiD· 1 shared Jing LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Aadil AhmedORCID

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1 paper

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedAug 6, 2025

IgG autoantibodies in bullous pemphigoid directly induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes:

Lei Bao, Christian Fernando Guerrero‐Juarez, Jing Li…·Kyle T. Amber

This study shows that BP-IgG autoantibodies induce a pro-inflammatory response in keratinocytes via MyD88-dependent signaling, contributing to BP pathology.

11 citationstop 3%

humanbulk RNA-seq

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