Christian Fernando Guerrero‐Juarez

This study shows that BP-IgG autoantibodies induce a pro-inflammatory response in keratinocytes via MyD88-dependent signaling, contributing to BP pathology.

The paper identifies Sfrp2 as a multifunctional regulator controlling coat pattern and color in African striped mice through transcriptomics, modeling, and gene editing.

CellChat infers communication probabilities between cell groups using a mass-action model and 2,021 curated ligand-receptor interactions (multimeric complexes, cofactors), then compares signaling networks across scRNA-seq datasets.

The paper uses single-cell RNA sequencing to identify spatially distinct basal stem cell populations in human epidermis and shows their role in maintaining epidermal homeostasis through signaling and differentiation.