Author

Marina C. Garassino

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Christine M. BestvinaiD· 2 shared Alessandra EspositoiD· 1 shared Alexander GuzzettaiD· 1 shared Aliya HusainiD· 1 shared Alpaslan TasdoganiD· 1 shared Anna Di LelloiD· 1 shared Apameh Pezeshk· 1 shared Arjun RamaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Christine M. BestvinaORCID

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2 papers

Recent·Most cited

MCT1 activity defines an aggressive metabolic phenotype and therapeutic target in non-small cell lung cancer

Robert B Cameron, Kristen Erika Shema, Nathan Dubois, Maia G. Clare, Nia G. Hammond, Mayher Kaur, Brianna K. Chang, Elyse G. Schechter, Juliya Hsiang, Zuzanna Marczenia, Marina C. Garassino, Ling Cai, Christine M. Bestvina, Thomas P. Mathews, Alpaslan Tasdogan, , Brandon Faubert

This study shows that MCT1-mediated lactate uptake sustains nucleotide homeostasis in NSCLC, and its inhibition enhances chemotherapy efficacy by exposing a metabolic vulnerability.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapy

Vivek Behera, Alexander Guzzetta, Hannah Giba, Ue-Yu Pen, Anna Di Lello, Bipul Pandey, Benjamin A. Doran, Alessandra Esposito, Apameh Pezeshk, Aliya Husain, Christine M. Bestvina, Justin Paul Kline, Marina C. Garassino, Arjun Raman

This study identifies conserved spatial structures in tumors that predict immune response, using a classification framework based on transcriptional covariation.

Cell Reports Medicine · Aug 28, 2026Peer-reviewedCancer Biology