Riqiang Yan

The paper shows oligodendrocytes contribute to amyloid-β plaques in Alzheimer's disease, but neurons are required for plaque formation.

This study shows that loss of TDP-43 in brain endothelial cells causes blood-brain barrier defects in mouse models of ALS and FTD.

The paper identifies loss of nuclear TDP-43 in endothelial cells as a mediator of BBB signaling pathway dysfunction in neurodegenerative diseases using inCITE-seq.