Andrew Octavian Sasmita

This study shows that AP2 complex is essential for myelin sheath biogenesis and homeostasis, with loss of AP2 causing hypomyelination and hypermyelination in different developmental stages.

The paper shows oligodendrocytes contribute to amyloid-β plaques in Alzheimer's disease, but neurons are required for plaque formation.

This study shows that ageing-related myelin dysfunction drives amyloid-beta deposition in Alzheimer's disease mouse models, suggesting myelin integrity as an upstream risk factor.

This study shows that forebrain-specific myelin loss in mice causes catatonia-like symptoms and isolated executive dysfunction without affecting motor-sensory functions.

The paper demonstrates that oligodendrocytes mediate axo-vascular coupling in the mouse optic nerve by regulating vascular dilation in response to axonal activity.

The paper shows that neuronal cholesterol synthesis is critical for remyelination in chronic demyelination models and MS patients.