Amy L. Kimble

Endothelial Immunosuppression in Atherosclerosis : Translational Control by Elavl1/HuR

This paper shows that endothelial cells suppress CD8 T cell responses in atherosclerosis via Elavl1-regulated translational control of immune-regulatory proteins.

Endothelial PTBP1 Deletion in Transplanted Cardiac Tissue Limits Cardiac Allograft Vasculopathy

This study identifies PTBP1 as a key regulator of endothelial dysfunction in cardiac allograft vasculopathy, showing its deletion reduces fibrosis and immune activation in mouse models.

Cyp7b1-inhibiting azoles as novel enhancers of hematopoietic stem and progenitor cell mobilization

This paper identifies Cyp7b1-inhibiting azoles as enhancers of HSPC mobilization, particularly effective in SCD patients.

Loss of Endothelial TDP-43 Leads to Blood Brain Barrier Defects in Mouse Models of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

This study shows that loss of TDP-43 in brain endothelial cells causes blood-brain barrier defects in mouse models of ALS and FTD.

Targeted inCITE-Seq Analysis Identifies the Loss of Nuclear TDP-43 in Endothelium as a Mediator of Blood Brain Barrier Signaling Pathway Dysfunction in Neurodegeneration

The paper identifies loss of nuclear TDP-43 in endothelial cells as a mediator of BBB signaling pathway dysfunction in neurodegenerative diseases using inCITE-seq.