Author

Jordan D. Tyburski

University of ConnecticutORCID 0000-0002-2450-1649Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Amy L. KimbleiD· 2 shared Bo ReeseiD· 2 shared Cheemala AshokiD· 2 shared Evan R. JellisoniD· 2 shared Patrick A. MurphyiD· 2 shared Riqiang YaniD· 2 shared Aamir R. ZuberiiD· 1 shared Bing HaoiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Amy L. KimbleORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 13, 2023

Loss of Endothelial TDP-43 Leads to Blood Brain Barrier Defects in Mouse Models of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Cheemala Ashok, Amy L. Kimble, Jordan D. Tyburski…·Patrick A. Murphy

This study shows that loss of TDP-43 in brain endothelial cells causes blood-brain barrier defects in mouse models of ALS and FTD.

14 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 13, 2023

Targeted inCITE-Seq Analysis Identifies the Loss of Nuclear TDP-43 in Endothelium as a Mediator of Blood Brain Barrier Signaling Pathway Dysfunction in Neurodegeneration

Omar M. Omar, Amy L. Kimble, Cheemala Ashok…·Patrick A. Murphy

The paper identifies loss of nuclear TDP-43 in endothelial cells as a mediator of BBB signaling pathway dysfunction in neurodegenerative diseases using inCITE-seq.

3 citations

𝕏 PostBluesky