MicrobiologyPLoS PathogensPeer-reviewed
N -acetylglucosamine supplementation fails to bypass the critical acetylation of glucosamine-6-phosphate required for Toxoplasma gondii replication and invasion
María Pía Alberione, Víctor González‐Ruiz, Olivier von Rohr…·Joachim Kloehn
This study shows that N-acetylglucosamine supplementation cannot restore UDP-GlcNAc levels or function in T. gondii when GNA1 is depleted, highlighting the critical role of GlcN6P acetylation in parasite replication and invasion.
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