Luís Izquierdo

Hexosamine Biosynthesis Disruption Impairs GPI Production and Arrests Plasmodium falciparum Growth at Schizont Stages

This study shows that disrupting the hexosamine biosynthetic pathway in Plasmodium falciparum blocks GPI production, arrests parasite growth, and prevents egress from host cells.

Minimal impact of ivermectin on immune response and transcriptional profiles in naïve adults with mild COVID-19

This study evaluates the immunomodulatory effects of ivermectin in mild COVID-19 patients and finds no significant immune response changes, consistent with clinical trial results.

Inter-individual and inter-regional variability of breast milk antibody reactivity to bacterial lipopolysaccharides

The paper examines variability in breast milk antibody reactivity to bacterial lipopolysaccharides between rural Kenya and urban Switzerland, finding broad reactivity in Kenya and cross-reactivity with parasitic pathogens.