Author

Aditi Upadhye

University of Illinois ChicagoORCID 0000-0001-7204-6276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jalees RehmaniD· 2 shared Athulith Nemakal· 1 shared Balaji B. GaneshiD· 1 shared Bellur S. PrabhakariD· 1 shared Dylan SchwartziD· 1 shared Elie Abi KhaliliD· 1 shared Jeffrey R. JacobsoniD· 1 shared Jerry A. KrishnaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

Jalees RehmanORCID

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2 papers

Recent·Most cited

NicheProt: Cell-type-resolved proteomics of tissue compartments

Yi-Chien Wu, Dylan Schwartz, Elie Abi Khalil, Aditi Upadhye, Jalees Rehman, Seung Young Lee

NicheProt enables cell-type and microregion-resolved proteomic analysis by isolating specific cells from defined tissue compartments using 3D microscopy and photobleaching-mediated barcoding.

Science Advances · Jul 15, 2026Peer-reviewedSystems Biology

Persistent Immune Dysregulation during Post-Acute Sequelae of COVID-19 is Manifested in Antibodies Targeting Envelope and Nucleocapsid Proteins

Marcin Kwissa, Manikannan Mathayan, Satyajeet S. Salunkhe, Velavan Bakthavachalam, Zijing Ye, Mark A. Sanborn, Samantha Condo, Aditi Upadhye, Athulith Nemakal, Justin M. Richner, Sanjib Basu, Richard M. Novak, Jeffrey R. Jacobson, Balaji B. Ganesh, Martha Cerda, , Jalees Rehman

This study examines immune dysregulation in Long COVID patients, finding persistent elevated anti-envelope and nucleocapsid antibodies and increased autoantibodies over six months.

bioRxiv · Aug 18, 2025 · PreprintImmunology