Xianfeng Wang

This study identifies leptin as a peripheral signal that modulates steroidogenesis by altering lipid pools through JAK/STAT signaling across species.

This study shows that polyploidy, induced by Notch signaling, enables epithelial cells to become non-professional phagocytes during stress, facilitating phagocytic functions essential for tissue homeostasis.

This study identifies Topoisomerase I as a conserved regulator of satellite DNA transcription across species, showing its role in centromere function and DNA damage response.

This study uses single-cell RNA sequencing to analyze the adult Drosophila ovary, identifying transcriptional programs that govern oogenesis and revealing new genetic markers and transcriptional signatures.