Author

Aiguo Tian

Tulane UniversityORCID 0000-0001-5011-6034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

Di Tian· 1 shared Hong LiuiD· 1 shared Jin JiangiD· 1 shared Lu YangiD· 1 shared Mengjie Li· 1 shared Qian ZhangiD· 1 shared Wu‐Min DengiD· 1 shared Xianfeng WangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Di Tian

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2 papers

Recent·Most cited

Developmental BiologyeLifePeer-reviewedApr 9, 2025

Numb provides a fail-safe mechanism for intestinal stem cell self-renewal in adult Drosophila midgut

Mengjie Li, Aiguo Tian, Jin Jiang

The paper shows that Numb acts alongside BMP signaling to ensure robust intestinal stem cell self-renewal in Drosophila midgut, particularly when BMP signaling is compromised.

4 citations

Drosophilaexperimental assay

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Cell BiologyNature CommunicationsPeer-reviewedJun 17, 2024

Topoisomerase I is an Evolutionarily Conserved Key Regulator for Satellite DNA Transcription

Zhen Teng, Lu Yang, Qian Zhang…·Hong Liu

This study identifies Topoisomerase I as a conserved regulator of satellite DNA transcription across species, showing its role in centromere function and DNA damage response.

12 citations

humanmouse

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