NeuroscienceEBioMedicinePeer-reviewed
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
Xuexin Li, Ivó H. Hernández, Seda Koyuncu…·Óscar Fernández-Capetillo
The paper identifies clofazimine as a drug that reduces polyQ toxicity by activating PPARγ, improving mitochondrial function in models of polyQ diseases.
5 citations