Author

Xuexin Li

Science for Life LaboratoryORCID 0000-0001-5824-9720Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xuexin Li1 paper · Department of General Surgery, The Fourth Affiliated Hospital, China Medical University, Shenyang, Liaoning 110032, China; Department of Physiology and Pharmacology, Karolinska Institutet, 171 65 Solna, Sweden

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Daniela Hühn· 2 shared Óscar Fernández-CapetilloiD· 2 shared Anikó GöblösiD· 1 shared Anna Anoir AbbasiD· 1 shared Balázs Kis· 1 shared Bendegúz SramkóiD· 1 shared David Vı́lcheziD· 1 shared Ivó H. HernándeziD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Daniela Hühn

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2 papers

Recent·Most cited

NeuroscienceEBioMedicinePeer-reviewedMay 1, 2024

The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

Xuexin Li, Ivó H. Hernández, Seda Koyuncu…·Óscar Fernández-Capetillo

The paper identifies clofazimine as a drug that reduces polyQ toxicity by activating PPARγ, improving mitochondrial function in models of polyQ diseases.

5 citations

zebrafishexperimental assay

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BioinformaticsbioRxivPreprintMar 10, 2023

The Drug Repurposing Encyclopedia (DRE): a web server for systematic drug repurposing across 20 organisms

Xuexin Li, Lu Pan, Laura Sanchez‐Burgos…·Óscar Fernández-Capetillo

The paper introduces DRE, a web server that enables drug repurposing analyses across 20 organisms using 198 million drug-signature associations.

4 citations

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