Federica Bertocchini

This paper shows that metabolic overflow, such as acetate excretion, prevents ecological collapse in microbial populations by slowing growth and coordinating population responses.

This paper challenges the conventional view of HIFs as mediators of hypoxic stress, proposing instead that HIFs prevent hypoxia by regulating electron transport and redefining the Warburg effect as a homeostatic response to metabolic demand.

This paper introduces a modeling framework for homeostatic regulation that integrates biological context and signal dynamics, challenging traditional engineering control theory approaches.

The paper identifies two enzymes in wax worm saliva that oxidize and depolymerize polyethylene, overcoming a key bottleneck in plastic biodegradation.

The paper evaluates microbiome analyses by generating virtualomes to reveal limitations in current methods and confirms findings using Galleria mellonella larvae.