Author

Jessica D. Tolbert

Dartmouth CollegeORCID 0000-0001-7243-1684Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

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Charles R. MidgettiD· 1 shared Christopher M. BollingeriD· 1 shared F. Jon KulliD· 1 shared George P. MunsoniD· 1 shared Kacey Marie TalbotiD· 1 shared

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1 shared paperMicrobiology

Charles R. MidgettORCID

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1 paper

Recent·Most cited

MicrobiologymSpherePeer-reviewedJul 24, 2025

Characterization of the ligand binding pocket of the virulence regulator Rns, a Member of the AraC/XylS family of transcription factors

Jessica D. Tolbert, Kacey Marie Talbot, Christopher M. Bollinger…·Charles R. Midgett

This study identifies key residues in the Rns binding pocket critical for fatty acid inhibition and structural rigidity, supporting the hypothesis that fatty acid binding inhibits AraC regulators in bacterial pathogens.

DOI 10.1128/msphere.00115-25

E. colistructural biology

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