Author

Ya-Chen Cheng

Oregon Health & Science UniversityORCID 0000-0001-7252-7651Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Marc R. FreemaniD· 2 shared A. A. AvetisyaniD· 1 shared Amanda JeffersoniD· 1 shared Amy E. SheehaniD· 1 shared Katherine S. LehmanniD· 1 shared Kevin A. SwiftiD· 1 shared Madison T HuppiD· 1 shared Paul MeraneriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Marc R. FreemanORCID

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2 papers

Recent·Most cited

NeuroscienceCell ReportsPeer-reviewedJan 22, 2026

Hypoxia-inducible factor 1 protects neurons from Sarm1-mediated neurodegeneration

Paul Meraner, A. A. Avetisyan, Kevin A. Swift…·Marc R. Freeman

The paper identifies HIF-1 as a regulator of Sarm1-mediated neurodegeneration, showing that stabilized HIF-1 prevents NAD+ loss and protects neurons.

1 citation

humanDrosophila

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NeurosciencebioRxivPreprintDec 5, 2023

Astrocyte-dependent local neurite pruning and Hox gene-mediated cell death in Beat-Va neurons

Katherine S. Lehmann, Madison T Hupp, Amanda Jefferson…·Marc R Freeman

The paper identifies two neuronal subtypes in Drosophila that undergo distinct remodeling processes during metamorphosis, highlighting astrocyte-dependent pruning and Hox gene-mediated cell death.

DOI 10.1101/2023.12.05.570324

Drosophilaexperimental assay

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