ImmunologyImmunityPeer-reviewed
Diverse priming outcomes under conditions of very rare precursor B cells
Patrick J. Madden, Ester Marina-Zárate, Kristen A. Rodrigues…·Shane Crotty
The paper investigates how vaccine antigen delivery and adjuvant selection affect the priming of rare HIV broadly neutralizing antibody-precursor B cells in non-human primates, finding that specific dosing and adjuvant combinations enhance their detection in germinal centers.
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