Sebastián Real

The paper identifies left-right asymmetry in breast tumor microenvironments linked to bioelectric and epigenetic differences, revealing a new layer of tumor heterogeneity.

This study shows that targeting nuclear DNA methylation can selectively reduce heteroplasmy in mitochondrial diseases by impairing high-heteroplasmy cells.

This study identifies ID4 as a driver of aggressive basal-like breast cancer and shows that its inhibition reduces tumor growth and metastasis, suggesting it as a therapeutic target.